Emerging Trends in Spatial Biomarker Analysis
What Does Spatial Biology Require in Clinical Trials?
— Initiatives by Navigate BioPharma × Orion HT —
Accurately resolving the tissue microenvironment has long been a major challenge.
Specifically, obtaining critical information such as “which cell types are present,” “in what quantity,” and “in what functional state” at the level required for clinical trials—namely, biomarker depth, data quality, and throughput—has not been straightforward.
To address these challenges, Navigate BioPharma—one of the leading CROs in precision medicine and a subsidiary of Novartis—has adopted Orion HT for its spatial biology service offerings.
Why Orion HT?
Orion is a spatial analysis platform based on multiplex immunofluorescence, capable of meeting the key requirements of clinical trials:
- High-plex analysis (up to 17 markers simultaneously)
- Compatibility with FFPE tissues (highly aligned with standard pathology workflows)
- High-throughput and highly reproducible data acquisition
This enables spatially resolved and quantitative biomarker analysis, which has traditionally been difficult to achieve, at a clinical trial-ready level.
What You Will Learn in This Webinar
In this webinar, real-world operational use cases from Navigate BioPharma will be presented, covering the following topics:
- Validation strategies for 17-plex panels across multiple tumor indications
- Why Orion is well-suited for modern therapeutic development and clinical trials
- A fast, flexible, and reliable panel design workflow
Webinar Overview
Spatial Biomarker Panels for Clinical Trials
<Speakers>
Jennifer Bordeaux, PhD
Associate Director, Digital Pathology Solutions, Navigate BioPharma Services
Tad George, PhD
Senior Vice President, Biology R&D, RareCyte
This webinar provides insights into how spatial biomarker analysis is implemented in real clinical trials, as well as its scientific and practical significance.
Date & Time: March 19, 2026, 2:00 AM (JST)
(Eastern Time: March 18, 2026, 1:00 PM / Pacific Time: 10:00 AM)
Registration
To participate in this webinar, please register in advance via the link below:
Register Here (RareCyte)
